Heartworm disease is described in a 14-month-old neutered female ferret (Mu
stela putorius furo) which had a three-week history of sneezing, anorexia a
nd dyspnoea, Echocardiography revealed the presence of heartworms as hypere
choic densities within the right atrial and ventricular cavities. At necrop
sy, four Dirofilaria immitis parasites (three females, one male) were found
in the right heart, the cranial vena cava and the caudal vena cava. Histop
athological findings were similar to those reported in canine heartworm dis
ease. Echocardiography may be a useful method of diagnosis of heartworm dis
ease in the ferret.