MR spectroscopy, T-2 relaxometry, and postoperative prognosis in cryptogenic temporal lobe epilepsy

The preoperative localization of pharmacoresistant focal epilepsies before surgery and the prognosis concerning seizure outcome are both of importance . In addition to conventional MRI diagnostics for the detection of small ep ileptogenic lesions, proton magnetic resonance spectroscopic imaging (HMR s pectroscopy) can be useful for assessing the bilaterality of pathological c hanges in cryptogenic temporal lobe epilepsies. The technique and findings of HMR spectroscopy are reported in patients with cryptogenic temporal lobe epilepsies. The findings indicate that chemical shift imaging (CSI) invest igations of the ipsilateral and contralateral hemispheres provide important information for the prediction of seizure outcome after epilepsy surgery.