Speech disorder and dyskinesia as initial symptoms in corticobasal degeneration

The article describes the development of symptoms in a 59-year-old patient. Dyskinesia and speech disorder were the only clinical features in the begi nning. Increased immunological parameters and only slight hypokinetic-rigid signs for a long time made the diagnostical and therapeutical process more difficult,as well as atypical findings in neuroimaging techniques. Cortico basal degeneration was diagnosed about 6 years after onset of clinical symp toms.