Local intra-arterial lysis using recombinant tissue plasminogen activator (
rTPA) was performed in a 6 and 2/3-year-old patient with major cardioemboli
c ischemic stroke 48 hours after intracardiac surgery. Selective applicatio
n of 2.5 mg rTPA (0.11 mg/kg body weight) resulted in recanalization of the
occluded cerebral vasculature with good neurologic recovery.