Lymphocyte inclusions in Finnish-variant late infantile neuronal ceroid lipofuscinosis (CLN5)

Authors
Rapola, J Lake, BD
Citation
J. Rapola et Bd. Lake, Lymphocyte inclusions in Finnish-variant late infantile neuronal ceroid lipofuscinosis (CLN5), NEUROPEDIAT, 31(1), 2000, pp. 33-34
Citations number
10
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROPEDIATRICS
ISSN journal
0174304X → ACNP
Volume
31
Issue
1
Year of publication
2000
Pages
33 - 34
Database
ISI
SICI code
0174-304X(200002)31:1<33:LIIFLI>2.0.ZU;2-M
Abstract
Electron microscopic reinvestigation of archival samples of peripheral bloo d lymphocytes of four patients with Finnish-variant late infantile neuronal ceroid lipofuscinosis (CLN5) showed inclusions with dark globules and part icles showing fingerprint profiles. Findings, in contrast to an earlier rep ort, show that the lymphocytes in this disease carry pathognomonic cytosome s like all other forms of neuronal ceroid lipofuscinosis in childhood.