The author presents a brief review Of the methodologies of outcomes analysi
s. Recent large database outcomes studies on patients undergoing carotid en
darterectomy are also reviewed and compared with the data generated from tw
o prospective randomized studies, and large database outcomes analysis are
discussed, The efforts of the American Association of Neurological Surgeons
and the Congress of Neurological Surgeons Outcomes Committee to perform on
line, multicenter outcomes studies are reviewed.