A 17-year-old girl with a 9-month history of papulopustular acne developed
disfiguring, highly inflammatory, fluctuant nodules in both nasolabial fold
s within 2 months. Periodically she experienced discharge of pus and blood
from these lesions. A diagnosis of disfiguring draining sinus tracts associ
ated with acne vulgaris was made. The therapeutic regimen included intrales
ional corticosteroid injection, systemic corticosteroids along with a macro
lide antibiotic, and systemic isotretinoin to reduce the inflammatory proce
ss. Outcome was favorable, with no recurrences during the following 10 mont
hs. Draining sinus is a malevolent lesion usually seen in severe forms of a
cne such as acne conglobata, acne fulminans, and acne inverse. Treatment is
difficult and often unsatisfactory. In many cases, excision of the lesion
is necessary to provide a permanent cure.