Severe fetal cytomegalic inclusion disease after documented maternal reactivation of cytomegalovirus infection during pregnancy

Recurrent cytomegalovirus infection during pregnancy is considered less dan gerous for the fetus than primary infection. We present a case of severe fe tal cytomegalic inclusion disease after maternal reactivation of cytomegalo virus during the first trimester of pregnancy. The possibility of such feta l injury is an argument for prenatal diagnosis in seropositive pregnant wom en when ultrasonographic findings suggest cytomegalovirus infection. Copyri ght (C) 2000 John Wiley & Sons, Ltd.