PURPOSE: To prospectively evaluate iliac angle and iliac length in a large
number of normal fetuses and to identify factors that may influence these m
easurements.
MATERIALS AND METHODS: At antenatal ultrasonography (US) in 356 fetuses, th
e iliac angle and iliac length were measured at two axial levels (superior
and inferior). In mixed linear models,the statistical significance and magn
itude of effect on the measurement of iliac angle and iliac length were est
imated for gestational age, fetal sex, maternal diabetes status, axial leve
l, and spine position relative to the transducer.
RESULTS: Statistically significant effects were found for gestational age,
axial level, and spire orientation but not for fetal sex or maternal diabet
es status. The iliac angle was found to decrease by 15.7 degrees from the s
uperior to inferior portion of the pelvis, decrease by approximately 0.37 d
egrees/wk, and decrease by as much as 15.6 degrees when the spine is direct
ed to the side. Iliac length was found to increase by 0.8 mm/wk from 13 wee
ks to term, decrease by 1.2 mm from the superior to the inferior portion of
the pelvis, and increase by as much as 1.29 mm when the spine is not direc
tly subjacent to the transducer.
CONCLUSION: The axial level of measurement, gestational age, and spine orie
ntation must be accounted for if these morphometric indexes are used to dis
criminate fetuses with and those without Down syndrome.