A new asymmetric route to substituted piperidines: synthesis of N-alkyl-3,4-dihydroxy-5-alkylpiperidines

Authors
Sun, HB Millar, KM Yang, JS Abboud, K Horenstein, BA
Citation
Hb. Sun et al., A new asymmetric route to substituted piperidines: synthesis of N-alkyl-3,4-dihydroxy-5-alkylpiperidines, TETRAHEDR L, 41(16), 2000, pp. 2801-2804
Citations number
10
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
16
Year of publication
2000
Pages
2801 - 2804
Database
ISI
SICI code
0040-4039(20000415)41:16<2801:ANARTS>2.0.ZU;2-2
Abstract
A facile asymmetric synthesis of N-alkyl-3,4-dihydroxy-5-alkylpiperidines h as been developed, which is based on an asymmetric alkylation reaction of t he SAMP hydrazone of N-BOC piperidinone. (C) 2000 Elsevier Science Ltd. All rights reserved.