Synthesis of alkaloids from amino acids via N-acyliminium ions generated by one-pot radical decarboxylation-oxidation

Authors
Boto, A Hernandez, R Suarez, E
Citation
A. Boto et al., Synthesis of alkaloids from amino acids via N-acyliminium ions generated by one-pot radical decarboxylation-oxidation, TETRAHEDR L, 41(16), 2000, pp. 2899-2902
Citations number
32
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
16
Year of publication
2000
Pages
2899 - 2902
Database
ISI
SICI code
0040-4039(20000415)41:16<2899:SOAFAA>2.0.ZU;2-I
Abstract
A one-pot methodology for the synthesis of alpha-substituted nitrogen heter ocycles from commercial amino acids has been developed. Good stereoselectiv ity can be achieved with chiral substituted rings. This procedure has been applied to the synthesis of piperidine, pyrrolidine and indolizidinone alka loids. (C) 2000 Elsevier Science Ltd. All rights reserved.