A. Boto et al., Synthesis of alkaloids from amino acids via N-acyliminium ions generated by one-pot radical decarboxylation-oxidation, TETRAHEDR L, 41(16), 2000, pp. 2899-2902
A one-pot methodology for the synthesis of alpha-substituted nitrogen heter
ocycles from commercial amino acids has been developed. Good stereoselectiv
ity can be achieved with chiral substituted rings. This procedure has been
applied to the synthesis of piperidine, pyrrolidine and indolizidinone alka
loids. (C) 2000 Elsevier Science Ltd. All rights reserved.