Alternative base matrices for solid phase quenching reagents

Authors
Nicewonger, RB Ditto, L Varady, L
Citation
Rb. Nicewonger et al., Alternative base matrices for solid phase quenching reagents, TETRAHEDR L, 41(14), 2000, pp. 2323-2326
Citations number
6
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
14
Year of publication
2000
Pages
2323 - 2326
Database
ISI
SICI code
0040-4039(20000401)41:14<2323:ABMFSP>2.0.ZU;2-E
Abstract
In this paper we describe the use of macroporous, highly cross-linked poly( styrene-divinylbenzene) as a base matrix for solid phase scavengers. We dem onstrate that this matrix is superior to the more traditional Merrifield re sins when non-swelling solvents like acetonitrile are used. A small library of sulfonamides is generated in high purity as an example. (C) 2000 Elsevi er Science Ltd. All rights reserved.