Silver salt-promoted direct cross-coupling reactions of alkynylsilanes with aryl iodides: synthesis of aryl-substituted alkynylamides

Authors
Koseki, Y Omino, K Anzai, S Nagasaka, T
Citation
Y. Koseki et al., Silver salt-promoted direct cross-coupling reactions of alkynylsilanes with aryl iodides: synthesis of aryl-substituted alkynylamides, TETRAHEDR L, 41(14), 2000, pp. 2377-2380
Citations number
23
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
14
Year of publication
2000
Pages
2377 - 2380
Database
ISI
SICI code
0040-4039(20000401)41:14<2377:SSDCRO>2.0.ZU;2-M
Abstract
A direct cross-coupling reaction of 5-trimethylsilyl-4-pentynamides (alkyny lsilanes) 1 with aryl iodides, promoted by silver carbonate in the presence of palladium catalyst, afforded aryl-substituted alkynylamides 2, which re adily underwent cyclization to form benzylidenelactams 3. This coupling rea ction proved to be a useful for synthesis of aryl-substituted alkynes. (C) 2000 Elsevier Science Ltd. All rights reserved.