A new technique for the measurement in fluids of the acoustic non-linearity
parameter BIA is presented, together with measured BIA values for several
fluids. The non-linearity parameter is measured by phase locking radial mod
es within a PZT cylinder. The system, which implements the isentropic phase
technique, uses continuous wave phase locking to measure the change in sou
nd velocity that is typically associated with a change in ambient pressure
under constant entropy. The method provides a means of measuring BIA in vit
ro both accurately and simply without the typical problems involved in time
-of-flight systems. Fluid samples can remain small due to the nature of the
cavity resonator, so the system is well suited to small volume, biological
samples. (C) 2000 Elsevier Science B.V. All rights reserved.