A retrospective analysis of invasive Streptococcus pneumoniae infections in Trinidad

A retrospective analysis of culture-positive cases of S pneumoniae from nor mally sterile body fluids is reported Over 40% of patients were 5 years old or less while 28% of patients were 50 years old or more. Meningitis (44%) was the commonest clinical presentation followed closely by pneumonia (31%) . The commonest predisposing disorder was human immunodeficiency virus infe ction though there were no identifiable risk factors in the majority, of pa tients. Mortality from invasive pneumococcal disease was significantly, hig her in elderly patients compared with other age groups (p=0.0003). In this study, all S pneumoniae isolates, for which there were antibiotic sensitivi ty data, were penicillin and/or amoxycillin sensitive.