Systemic phaeohyphomycosis in pregnancy and the puerperium

Systemic fungal infections are rave. In pregnancy, treatment is problematic because of the risk of possible teratogenic effects of the antifungal drug s. We present the case of a 32 year-old woman who presented during pregnanc y with a two-month history, of painless subcutaneous nodules. Excision biop sy, of one lesion showed dematiaceous fungal elements. Anti-fungal treatmen t was deferred al td the pregnancy proceeded uneventfully. The remaining no dules were excised at the time of caesarean section delivery. Three weeks i nto the puerperium, she developed generalised seizures and investigations i ndicated systemic fungal infection with positive cultures for Aureobasidium spp which responded to appropriate antifungal therapy of flucytosine and i traconazole.