A comprehensive web resource on RNA helicases from the baker's yeast Saccharomyces cerevisiae

Members of the RNA helicase protein family are defined by several motifs th at have been widely conserved during evolution. They are found in all organ isms-from bacteria to humans-and many viruses. The minimum number of RNA he licases present within a eukaryotic cell can be predicted from the complete sequence of the Saccharomyces cerevisiae genome. Recent progress in the fu nctional analysis of various family members has confirmed the significance of RNA helicases for most cellular RNA metabolic processes. We have assembl ed a web resource that focuses on RNA helicases from the budding yeast Sacc haromyces cerevisiae. It includes descriptions of RNA helicases and their f unctions, links to sequence- and yeast-specific databases, an extensive lis t of references, and links to non-yeast helicase web resources. Copyright ( C) 2000 John Wiley & Sons, Ltd.