Steroid 5 alpha-reductase inhibitory activity and hair regrowth effects ofan extract from Boehmeria nipononivea

Authors
Shimizu, K Kondo, R Sakai, K Shoyama, Y Sato, H Ueno, T
Citation
K. Shimizu et al., Steroid 5 alpha-reductase inhibitory activity and hair regrowth effects ofan extract from Boehmeria nipononivea, BIOS BIOT B, 64(4), 2000, pp. 875-877
Citations number
8
Categorie Soggetti
Agricultural Chemistry","Biochemistry & Biophysics
Journal title
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
ISSN journal
09168451 → ACNP
Volume
64
Issue
4
Year of publication
2000
Pages
875 - 877
Database
ISI
SICI code
0916-8451(200004)64:4<875:S5AIAA>2.0.ZU;2-D
Abstract
The acetone extract of Boehmeria nipononivea showed both potent 5 alpha-red uctase inhibitory activity and hair regrowth promotion effects on mice. 5 a lpha-Reductase inhibitory activity-guided fractionation led to six active f atty acids: alpha-linolenic, linoleic, palmitic, elaidic, oleic and stearic acids. The extract of B. nipononivea, and alpha-linolenic, elaidic and ste aric acids exhibited a hair regrowth effect.