Resolution and synthesis of optically active alcohols with immobilized water-soluble proteins from green pea, soybean and buckwheat as new bio-catalysts

Citation
H. Nagaoka et H. Kayahara, Resolution and synthesis of optically active alcohols with immobilized water-soluble proteins from green pea, soybean and buckwheat as new bio-catalysts, BIOS BIOT B, 64(4), 2000, pp. 781-784
Citations number
12
Categorie Soggetti
Agricultural Chemistry","Biochemistry & Biophysics
Journal title
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
ISSN journal
09168451 → ACNP
Volume
64
Issue
4
Year of publication
2000
Pages
781 - 784
Database
ISI
SICI code
0916-8451(200004)64:4<781:RASOOA>2.0.ZU;2-P
Abstract
Kinetic resolution of racemic alcohols, (+/-)-1-(4-substituted phenyl)ethan ol and (+/-)-1-(2-naphthyl)ethanol, was done with immobilized green pea, so ybean, or buckwheat proteins. The resolution was done stereoselectively by oxidizing only one enantiomer of a racemic alcohol to leave an optically ac tive alcohol with a high purity. In addition, each protein could be reused consecutively at least three times without any decrease of yield or optical purity.