Dependence of rat spot14 promoter activity on NF-Y binding to the invertedCCAAT-element at-100

Authors
Roder, K Wolf, SS Schweizer, M
Citation
K. Roder et al., Dependence of rat spot14 promoter activity on NF-Y binding to the invertedCCAAT-element at-100, BIOS BIOT B, 64(4), 2000, pp. 848-851
Citations number
3
Categorie Soggetti
Agricultural Chemistry","Biochemistry & Biophysics
Journal title
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
ISSN journal
09168451 → ACNP
Volume
64
Issue
4
Year of publication
2000
Pages
848 - 851
Database
ISI
SICI code
0916-8451(200004)64:4<848:DORSPA>2.0.ZU;2-Q
Abstract
Electrophoretic mobility Shift assay (EMSA) and in vitro transcription/tran slation show that NF-Y binds to the inverted CCAAT-element in the promoter of the rodent spot14 gene. The NF-Y-binding sequence has been shown to be r esponsible for basal activity in H4IIE. Given the similar role found for th e inverted CCAAT-element in the promoter of the FAS gene, NF-Y may have an important function in the control of lipogenesis.