One of the major limitations in coronary intervention is restenosis. This s
tudy was aimed to identify clinical, angiographic, and procedural factors t
hat may be related to the second restenosis (501, We studied 101 patients w
ho underwent more than two follow-up coronary angiograms after two coronary
interventions between January 1996 and December 1998 in Chonnam University
Hospital tout of 4,092 total coronary interventions in 3,030 patients duri
ng the same period). The patients were divided into two groups according to
the evidence of SR, Fifty-two patients (group A: 57 +/- 10 years, M:F = 44
:8) who had SR and the other 49 patients (group B: 54 +/- 9 years, M:F = 44
:5) without SR were analyzed. Clinical features, angiographic characteristi
cs, coronary interventional procedures, and other risk factors were compare
d between two groups by univariate analysis and multivariate stepwise logis
tic regression analysis was performed for the predictive factors for SR. Th
e clinical variables of age, sex, clinical diagnosis, and risk factors were
not different between two groups. The lesion severer than B-2 by AHA/ACC c
lassification were associated with SR (P < 0.05). Recurrent angina as an in
dication for follow-up angiography was associated with SR (P < 0.01). Predi
ctive factors associated with SR were patient's subjective symptom and lesi
on severer than type B, according to AHA/ACC classification. (C) 2000 Wiley
-Liss. Inc.