Unique sodium-caged structure of a potent endothelin-1 inhibitor: crystal structure of BQ123 sodium salt, cyclo(-D-Trp-D-Asp(-)-Pro-D-Val-Leu-)centerdot Na+

Authors
Doi, M Ishida, T Katsuya, Y Mezaki, Y Sasaki, M Terashima, A Taniguchi, T Hasegawa, H Shiono, M
Citation
M. Doi et al., Unique sodium-caged structure of a potent endothelin-1 inhibitor: crystal structure of BQ123 sodium salt, cyclo(-D-Trp-D-Asp(-)-Pro-D-Val-Leu-)centerdot Na+, CHEM COMMUN, (9), 2000, pp. 743-744
Citations number
15
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
9
Year of publication
2000
Pages
743 - 744
Database
ISI
SICI code
1359-7345(2000):9<743:USSOAP>2.0.ZU;2-K
Abstract
The crystal structure of cyclo(D-Trp-D-Asp(-)-Pro-D-Val-Leu-). Na+, a poten t endothelin-1 antagonist, showed four conformational isomers and two Na+-c aged structures in pairs.