Unusual reaction of azetidine-2,3-diones with primary amines. Straightforward asymmetric synthesis of alpha-amino acid and peptide derivatives

Authors
Alcaide, B Almendros, P Aragoncillo, C
Citation
B. Alcaide et al., Unusual reaction of azetidine-2,3-diones with primary amines. Straightforward asymmetric synthesis of alpha-amino acid and peptide derivatives, CHEM COMMUN, (9), 2000, pp. 757-758
Citations number
31
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
9
Year of publication
2000
Pages
757 - 758
Database
ISI
SICI code
1359-7345(2000):9<757:UROAWP>2.0.ZU;2-3
Abstract
An unprecedented one-step synthesis of unnatural alpha-amino acid and pepti de derivatives, in both the racemic and optically pure forms, using azetidi ne-2,3-diones as building blocks has been developed by treatment with prima ry amines.