This account highlights developments in the field of supramolecular tetrath
iafulvalene (TTF) chemistry. Progress in synthetic TTF chemistry during the
past decade has allowed the preparation of a number of elaborate molecular
systems based on host-guest interactions being able to act as either senso
rs, molecular switches or mediators for specific reactions. Among these sys
tems interlocked architectures such as rotaxanes and catenanes make a signi
ficant contribution.