Chromatography-free synthesis of 1,2,4-oxadiazoles using ROMPGEL-supportedacylating reagents

Authors
Barrett, AGM Cramp, SM Roberts, RS Zecri, FJ
Citation
Agm. Barrett et al., Chromatography-free synthesis of 1,2,4-oxadiazoles using ROMPGEL-supportedacylating reagents, COMB CHEM H, 3(2), 2000, pp. 131-138
Citations number
30
Categorie Soggetti
Chemistry & Analysis
Journal title
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
ISSN journal
13862073 → ACNP
Volume
3
Issue
2
Year of publication
2000
Pages
131 - 138
Database
ISI
SICI code
1386-2073(200004)3:2<131:CSO1UR>2.0.ZU;2-C
Abstract
1,2,4-Oxadiazoles were synthesized in solution from aromatic amidoximes and acylating agents supported on a ring opening metathesis polymer (ROMPGEL) backbone. High yields and purities of the 1,2,4-oxadiazoles were obtained w ith minimal purification.