Therapeutic use of chemokines

Chemokines are involved in a number of pathological processes, and therefor e represent important targets. However, it has also become apparent that ch emokines have exciting therapeutic applications in inflammatory, infectious and cancer-related diseases. The following review will highlight the appli cation of novel therapies including viral-encoded, recombinant, and genetic ally engineered chemokines to a number of diseases or disorders. Advances i n the application of novel chemokine delivery procedures both at the resear ch bench and the clinical bedside will also be discussed. Overall, the util ization of chemokines to prevent and treat disease has tremendous potential .