Gentle drugs: A new paradigm for drug development

Searching for new drugs is guided by their specificity and potency. The met hodology, including the statistical approaches, orients itself to do exactl y that. More potent drugs also have more side effects, a technology trap th at requires a radical re-examination regarding how to go about drug discove ry. It is relevant in an era when quality of life is emerging as more impor tant than the ill-kept promise of dramatic therapies. Interestingly, the pr oblem statement can be formalized and a strategy can be identified that req uires new methodological grounds to be covered within the scope of allopath y.