A new method for quality control of zinc pyritione pharmaceutical and cosmetic forms

Citation
P. Zubata et al., A new method for quality control of zinc pyritione pharmaceutical and cosmetic forms, DRUG DEV IN, 26(4), 2000, pp. 455-457
Citations number
10
Categorie Soggetti
Pharmacology & Toxicology
Journal title
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
ISSN journal
03639045 → ACNP
Volume
26
Issue
4
Year of publication
2000
Pages
455 - 457
Database
ISI
SICI code
0363-9045(2000)26:4<455:ANMFQC>2.0.ZU;2-6
Abstract
A simple high-performance liquid chromatographic (HPLC) method was develope d to determine zinc pyritione in pharmaceutical and cosmetic products. Reve rsed phase chromatography was conducted rising a C-18 column with an isocra tic mobile phase consisting of a suitable mixture of methanol acetonitrile, and water (30:2.5: 20). The effluent was monitored on a ultraviolet (UV) d etector at 243 nm. The method was validated following International Confere nce on Harmonisation (ICH) suggestions and proven accurate, precise, and sp ecific.