Citation
Y. Tanaka et Y. Harima, Oncoprotein expression predicts response to radiotherapy or thermoradiotherapy in human cervical cancer, EXP ONCOL, 22(1-2), 2000, pp. 52-58
Citations number
28
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
EXPERIMENTAL ONCOLOGY
ISSN journal
02043564
→ ACNP
Volume
22
Issue
1-2
Year of publication
2000
Pages
52 - 58
Database
ISI
SICI code
0204-3564(200003)22:1-2<52:OEPRTR>2.0.ZU;2-U
Abstract
The levels of Bax and Bcl-2 expression after 10.8 Gy radiotherapy are usefu
l prognostic markers in patients with human cervical carcinoma. Thermoradio
therapy was found to result in better treatment responses than radiotherapy
for patients with stage IIIB cervical carcinoma. An additive or synergisti
c antitumor effect of thermoradiotherapy is likely to occur through inducti
on of apoptosis involving one of the bax pathways.