Synthesis of 3-trifluoromethyl-3-aryldiazirines for photoaffinity-labelingprobes and their labeling ability

Authors
Morita, C Hashimoto, K Okuno, T Shirahama, H
Citation
C. Morita et al., Synthesis of 3-trifluoromethyl-3-aryldiazirines for photoaffinity-labelingprobes and their labeling ability, HETEROCYCLE, 52(3), 2000, pp. 1163
Citations number
10
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
52
Issue
3
Year of publication
2000
Database
ISI
SICI code
0385-5414(20000301)52:3<1163:SO3FP>2.0.ZU;2-4
Abstract
Photoaffinity-labeling probes of aryldiazirine derivatives with three subst ituents (diazirine, nitro, and alkyl or alkoxy) on C1, C2, and C4 of the be nzene nucleus were synthesized and their labeling abilities were tested. Am ong the synthetic compounds (4, 5, and 12), only 12 was appropriate for the photoaffinity probe.