A case report study of 72 consecutive emdogain-treated intrabony periodontal defects: Clinical and radiographic findings after 1 year

This case report study examined the effect adjunctive use of Emdogain in th e treatment of intrabony periodontal defects. Seventy-two consecutively tre ated defects in sixty-one patients were included. Efficacy of treatment was evaluated at 12 months by assessment of probing depth reduction, probing a ttachment level gain, and radiographic bone gain from standardized radiogra phs. initial packet depth averaged 8.3 mm, and the mean probing attachment level was 10.0 mm. The mean radiographic defect depth was 5.3 mm. At 12 mon ths, mean pocket depth reduction was 4.7 mm and mean probing attachment lev el gain was 4.2 mm. Radiographic bone level gain averaged 3.1 mm and defect fill averaged 70%. The only variables significantly affecting radiographic bone gain were bleeding on probing and smoking. It was concluded that Emdo gain treatment of one- and two-wailed intrabony defects in a periodontal pr actice will result in a clinically significant gain of probing attachment l evel and radiographic bone that is similar to that reported in controlled c linical trials.