Progress in Arabidopsis genome sequencing and functional genomics

Authors
Wambutt, R Murphy, G Volckaert, G Pohl, T Dusterhoft, A Stiekema, W Entian, KD Terryn, N Harris, B Ansorge, W Brandt, P Grivell, L Rieger, M Weichselgartner, M de Simone, V Obermaier, B Mache, R Muller, M Kreis, M Delseny, M Puigdomenech, P Watson, M Schmidtheini, T Reichert, B Portatelle, D Perez-Alonso, M Boutry, M Bancroft, I Vos, P Hoheisel, J Zimmermann, W Wedler, H Ridley, P Langham, SA McCullagh, B Bilham, L Robben, J Van der Schueren, J Grymonprez, B Chuang, YJ Vandenbussche, F Braeken, M Weltjens, I Voet, M Bastiaens, I Aert, R Defoor, E Weitzenegger, T Bothe, G Ramsperger, U Hilbert, H Braun, M Holzer, E Brandt, A Peters, S van Staveren, M Dirkse, W Mooijman, P Lankhorst, RK Rose, M Hauf, J Kotter, P Berneiser, S Hempel, S Feldpausch, M Lamberth, S Van den Daele, H De Keyser, A Buysshaert, C Gielen, J Villarroel, R De Clercq, R Van Montagu, M Rogers, J Cronin, A Quail, M Bray-Allen, S Clark, L Doggett, J Hall, S Kay, M Lennard, N McLay, K Mayes, R Pettett, A Rajandream, MA Lyne, M Benes, V Rechmann, S Borkova, D Blocker, H Scharfe, M Grimm, M Lohnert, TH Dose, S de Haan, M Maarse, A Schafer, M Muller-Auer, S Gabel, C Fuchs, M Fartmann, B Granderath, K Dauner, D Herzl, A Neumann, S Argiriou, A Vitale, D Liguori, R Piravandi, E Massenet, O Quigley, F Clabauld, G Mundlein, A Felber, R Schnabl, S Hiller, R Schmidt, W Lecharny, A Aubourg, S Gy, I Cooke, R Berger, C Monfort, A Casacuberta, E Gibbons, T Weber, N Vandenbol, M Bargues, M Terol, J Torres, A Perez-Perez, A Purnelle, B Bent, E Johnson, S Tacon, D Jesse, T Heijnen, L Schwarz, S Scholler, P Heber, S Bielke, C Frishmann, D Haase, D Lemcke, K Mewes, HW Stocker, S Zaccaria, P Mayer, K Schuller, C Bevan, M
Citation
R. Wambutt et al., Progress in Arabidopsis genome sequencing and functional genomics, J BIOTECH, 78(3), 2000, pp. 281-292
Citations number
34
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
JOURNAL OF BIOTECHNOLOGY
ISSN journal
01681656 → ACNP
Volume
78
Issue
3
Year of publication
2000
Pages
281 - 292
Database
ISI
SICI code
0168-1656(20000331)78:3<281:PIAGSA>2.0.ZU;2-R
Abstract
Arabidopsis thaliana has a relatively small genome of approximately 130 Mb containing about 10% repetitive DNA. Genome sequencing studies reveal a gen e-rich genome, predicted to contain approximately 25 000 genes spaced on av erage every 4.5 kb. Between 10 to 20% of the predicted genes occur as clust ers of related genes, indicating that local sequence duplication and subseq uent divergence generates a significant proportion of gene families. In add ition to gene families, repetitive sequences comprise individual and small clusters of two to three retroelements and other classes of smaller repeats . The clustering of highly repetitive elements is a striking feature of the A. thaliana genome emerging from sequence and other analyses. (C) 2000 Els evier Science B.V. All rights reserved.