AZT has become a mainstay drug in efforts to slow disease progression
in HIV-infected individuals. Further, recent evidence indicates that A
ZT use by pregnant infected women and their neonates may reduce the ri
sk of vertical transmission. In a study of HIV-infected women's treatm
ent-related behavior, attitudes toward the use of this drug were exami
ned. Data were gathered through unstructured interviewing techniques.
The data from the first 71 women accrued revealed that negative attitu
des towards its use were widely prevalent. Women viewed the drug as hi
ghly toxic, prescribed indiscriminately, inadequately tested in women
and minorities, promoted for the wrong reasons and inappropriate while
they were feeling well. The findings suggest that removing attitudina
l barriers to the use of AZT will be important to both primary and sec
ondary prevention efforts. (C) 1997 Elsevier Science Ltd.