Initially described in 1953, the concept of self-neglect is complex. Defini
tional problems exist because it can be redefined by changes in context. Th
is article examines the epidemiology, etiology detection, ethical/legal iss
ues, management/intervention, and outcome. Prevention is particularly diffi
cult given the nature of the problem, the poorly understood etiology, and t
he slow insidious progression of the syndrome before it reaches public atte
ntion. This complexity is compounded by the fact that respect for autonomy
and personal rights is given paramount importance over paternalism when an
intervention at an earlier stage could potentially result in a better outco
me.