PURPOSE: To determine the efficacy of high-resolution MR angiography f
or the prospective diagnosis of ruptured aneurysms in acute subarachno
id hemorrhage, METHODS: We used 3-D time-of-flight MR angiography with
a large image matrix (193 x 512 frequency-encoding steps), magnetizat
ion transfer saturation, and a variable flip-angle excitation (tilted
optimized nonsaturating excitation [TONE]) to study 28 patients with a
cute subarachnoid hemorrhage, The MR angiograms were compared with int
raarterial digital subtraction angiographic (IA-DSA) images. RESULTS:
Thirty-five (90%) of 39 aneurysms were detected prospectively with MR
angiography. At least one aneurysm was identified with MR angiography
in 25 (96%) of 26 patients with aneurysms proved by IA-DSA. Although f
our aneurysms were missed prospectively, three of these were detected
retrospectively with MR angiography. Six aneurysms (18%) of those evid
ent on MR angiograms were 3 mm or less in diameter, In one patient, ad
ditional targeted maximum intensity projections were greatly helpful f
or the ensuing IA-DSA by determining the optimizal projection angle by
which to depict a ruptured aneurysm that neither routine MR angiograp
hy nor routine IA-DSA detected, CONCLUSION: High-resolution MR angiogr
aphy may be a useful diagnostic technique for detecting ruptured aneur
ysms, even in patients with acute subarachnoid hemorrhage, Initial MR
angiography offers valuable and reliable information on ruptured aneur
ysms in acute subarachnoid hemorrhage, allowing the optimization of pr
ojection angles at conventional angiography.