A case report of primary T-cell lymphoma of the liver

The patient was a 50-year-old woman who presented intermittent mild fever w ith elevated liver enzymes far 12 years. The liver biopsy showed diffuse po rtal and sinusoidal involvement of lymphoid cells with minimal atypia and e pithelioid histiocytic granuloma formation. Subsequent bone marrow biopsy s howed lymphomatous involvement The lymphocytes infiltrating the liver were reactive for T-cell marker and showed TCR gamma gene rearrangement. The pat ient was diagnosed as primary peripheral T-cell lymphoma of the liver. Indo lent clinical course and resemblance with hepatitis were considered to be a rare and unique feature of this case.