Weber-Christian disease presenting with proptosis: A case report

Weber-Christian disease (WCD) is a rare inflammatory disease of adipose tis sue, which is characterized by painful cutaneous nodules and constitutional symptoms. Although any area of the body containing fat can be affected by WCD, the involvement of retrobulbar fat is uncommon and proptosis is a rare presenting manifestation. We report a case who presented with proptosis of the right eye which is accompanied by painful subcutaneous nodules, high f ever and myalgia. Biopsies of retrobulbar tissue and suprapubic nodule show ed lobular panniculitis with mixed cellular infiltration, mainly composed o f histiocytes and lymphocytes. He responded well to high-dose glucocorticoi d.