RENAL ANGIOTENSIN-CONVERTING ENZYME LOCALIZATION IN DIABETIC RATS ANDTHE EFFECT OF LOW-PROTEIN DIET

Authors
MIZUIRI S KOBAYASHI T YOSHIKAWA H MIYAGI M TANEGASHIMA M SAKAI K HAYASHI I FUSHIMI T HASEGAWA A
Citation
S. Mizuiri et al., RENAL ANGIOTENSIN-CONVERTING ENZYME LOCALIZATION IN DIABETIC RATS ANDTHE EFFECT OF LOW-PROTEIN DIET, Nephron, 76(2), 1997, pp. 186-191
Citations number
23
Categorie Soggetti
Urology & Nephrology
Journal title
Nephron → ACNP
ISSN journal
00282766
Volume
76
Issue
2
Year of publication
1997
Pages
186 - 191
Database
ISI
SICI code
0028-2766(1997)76:2<186:RAELID>2.0.ZU;2-Q
Abstract
Recent evidence suggests a role of angiotensin-converting enzyme (ACE) in diabetic nephropathy, The effect of diabetes and low protein diet on renal immunohistochemical ACE localization was studied in streptozo tocin-induced DM rats. Immunohistochemical ACE localization was reduce d in DM rats, and a low protein diet partially resolved this abnormali ty while inhibiting the progression of diabetic nephropathy.