Recognition and encapsulation of an electroactive guest within a dynamically folded polymer

Diaminotriazine-functionalized polymer 1 folds in nonpolar media into unimo lecular "micelles", in which the diaminotriazine units are inwardly directe d to form a polar pocket analogous to the active sites found in proteins. T o explore the possibility of site isolation within this pocket we synthesiz ed the redox active guest 6-ferrocenyluracil 2. Encapsulation of guest 2 by polymer 1 was established by NMR studies; functional site isolation was de monstrated through cyclic voltammetry studies.