Cells use phosphorylation/dephosphorylation mechanisms to regulate the acti
vity of several proteins required to transmit information from the cell sur
face to the nucleus. Recent studies have significantly increased our knowle
dge regarding the structure/function of one major regulator of cell phospho
rylation: protein phosphatase 2A (PP2A). This review will discuss the role
of PP2A in virology and parasitology. (C) 2000 Editions scientifiques er me
dicales Elsevier SAS.