Identification of microorganisms using superconducting tunnel junctions and time-of-flight mass spectrometry

Citation
Jn. Ullom et al., Identification of microorganisms using superconducting tunnel junctions and time-of-flight mass spectrometry, NUCL INST A, 444(1-2), 2000, pp. 385-388
Citations number
7
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences","Instrumentation & Measurement
Journal title
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT
ISSN journal
01689002 → ACNP
Volume
444
Issue
1-2
Year of publication
2000
Pages
385 - 388
Database
ISI
SICI code
0168-9002(20000411)444:1-2<385:IOMUST>2.0.ZU;2-C
Abstract
We present time-of-flight measurements of biological material ejected from bacterial spores following laser irradiation. Ion impacts are registered on a microchannel plate detector and on a Superconducting Tunnel Junction (ST J) detector. We compare mass spectra obtained with the two detectors. The S TJ has better sensitivity to massive ions and also measures the energy of e ach ion. We show evidence that spores of different bacillus species produce distinctive mass spectra and associate the observed mass peaks with coat p roteins. (C) 2000 Elsevier Science B.V. All rights reserved.