We introduce a new parameterization of four-fermion matrix elements which d
oes not involve quark masses and thus allows a reduction of systematic unce
rtainties in physical amplitudes. As a result the apparent quadratic depend
ence of epsilon'/epsilon On m(s)(mu) is removed. To simplify the matching b
etween lattice and continuum renormalization schemes, we express our result
s in terms of Renormalization Group Invariant B-parameters which are renorm
alization-scheme and scale independent. As an application of our proposal,
matrix elements of Delta I = 3/2 and SUSY Delta F = 2 (F = S, C, B) four-fe
rmion operators have been computed.