Non-specific noradrenaline reuptake inhibition by high dose selective serot
onin reuptake inhibitors, along with catecholamine release from phaeochromo
cytoma, may lead to a hypertensive paroxysm. This may unmask a clinically s
ilent phaeochromocytoma. Hypertensive paroxysm induced by paroxetine leadin
g to detection of phaeochromocytoma has been reported. The first patient in
whom fluoxetine unmasked a phaeochromocytoma is reported.