Copper catalyzed conjugate addition of highly functionalized arylmagnesiumcompounds to enones

Authors
Varchi, G Ricci, A Cahiez, G Knochel, P
Citation
G. Varchi et al., Copper catalyzed conjugate addition of highly functionalized arylmagnesiumcompounds to enones, TETRAHEDRON, 56(18), 2000, pp. 2727-2731
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
56
Issue
18
Year of publication
2000
Pages
2727 - 2731
Database
ISI
SICI code
0040-4020(20000428)56:18<2727:CCCAOH>2.0.ZU;2-N
Abstract
Highly functionalized arylmagnesium bromides are readily prepared by an iod ine-magnesium exchange reaction. In the presence of catalytic amounts of co pper(I) salts and chlorotrimethylsilane, they add to various enones leading to the conjugate addition products in 66-89% yield. (C) 2000 Elsevier Scie nce Ltd. All rights reserved.