Metastatic tumors of the spleen are rare and usually occur in the pres
ence of disseminated visceral metastases. The liver is the most common
site of metastatic spread from colon cancer. We report a case of isol
ated intrasplenic metastasis from sigmoid colon cancer and review the
possible reasons for the rarity of splenic metastasis. This represents
the fifth reported case of isolated splenic metastasis from colon can
cer. Splenectomy may be justified in presence of isolated metastatic d
isease, since it is an operation with a low complication rate and may
provide potential longterm survival in colon cancer.