We report an unusual case of Streptococcus pneumoniae sacroiliitis in
a previously healthy 31-year-old woman, Six cases of pneumococcal sacr
oiliitis have been reported; the only two cases in adults occurred in
young women in the preantibiotic era, Our patient had fever and a depr
essed level of consciousness, with subsequent right buttock and thigh
pain, Blood cultures revealed S pneumoniae, and a bone scan showed inc
reased tracer activity in the right sacroiliac joint. Although the cer
ebrospinal fluid white blood cell count was only 3/mu L, culture of ce
rebrospinal fluid grew S pneumoniae, Our patient was successfully trea
ted with a 6-week course of intravenous antibiotics (penicillin G afte
r an initial week of ceftriaxone), followed by 2 weeks of oral penicil
lin therapy.