A new cucurbitacin glycoside from Kageneckia oblonga (Rosaceae)

Citation
O. Munoz et al., A new cucurbitacin glycoside from Kageneckia oblonga (Rosaceae), Z NATURFO C, 55(3-4), 2000, pp. 141-145
Citations number
16
Categorie Soggetti
Biochemistry & Biophysics
Journal title
ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
ISSN journal
09395075 → ACNP
Volume
55
Issue
3-4
Year of publication
2000
Pages
141 - 145
Database
ISI
SICI code
0939-5075(200003/04)55:3-4<141:ANCGFK>2.0.ZU;2-0
Abstract
A novel cucurbitacin glycoside has been isolated from aerial parts of Kagen eckia oblonga R. et P. and shown to be 3 beta-(beta-D-glucosyloxy)-16 alpha ,23 alpha-epoxycucurbita-5,24-dien-11-one. The structure was established by usual spectroscopic and two-dimensional (2D) NMR techniques. This compound has found to be nontoxic when tested in-vivo cell culture assays. In previ ous investigations we reported 23,24-dihydrocucurbitacin F and prunasine. T his was the first report on cucurbitacins from the genus Kageneckia (Rosace ae).