GRANULOMA-ANNULARE

Granuloma annulare (GA) is a benign cutaneous lesion that has no prove n etiology or widely accepted theory of pathogenesis. It has several c linical manifestations and a multitude of differential diagnoses. This article reviews the common presentations of the disease, discusses cu rrent studies of the histology, pathogenesis, and etiology, and detail s effective treatment modalities, The eruption commonly resolves withi n 2 years; however, patients may desire treatment due to unacceptable cosmesis or irritation. knowledge of the clinical manifestations, the more common differential diagnoses, and the successful treatment plans , including cryosurgery, surgical excision, intralesional triamcinolon e, isotretinoin therapy, and PUVA therapy are necessary to provide pat ients with the most beneficial care.