Citation
Oa. Salomone et al., Prevalence of circulating Trypanosoma cruzi detected by polymerase chain reaction in patients with Chagas' cardiomyopathy, AM J CARD, 85(10), 2000, pp. 1274
Citations number
17
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149
→ ACNP
Volume
85
Issue
10
Year of publication
2000
Database
ISI
SICI code
0002-9149(20000515)85:10<1274:POCTCD>2.0.ZU;2-1
Abstract
Amplification of Trypanosoma cruzi deoxyribonucleic acid by the polymerase
chain reaction technique was performed in a clinically well-characterized g
roup of patients with chronic Chagas' disease. A significant association be
tween the presence of parasites and typical cardiac lesions was found, supp
orting an active role for Trypanosoma cruzi in the pathophysiologic mechani
sms leading to chronic Chagas' cardiomyopathy.