Adult herpetic laryngitis with concurrent candidal infection - A case report and literature review

Rarely, adult herpetic laryngitis without involvement of the oropharynx has been reported. However, to our knowledge, laryngitis caused by herpes simp lex virus with coexisting Candida albicans has not been reported. We report what we believe to be the first case of localized herpetic laryngitis supe rimposed by laryngeal Candida species infection in an immunosuppressed pati ent. This diagnosis was made on the basis of the findings of a laryngeal mu cosal biopsy and ancillary testing using fungal stains and immunohistochemi cal stains for herpetic antigens. We also review the literature and discuss the clinical and diagnostic presentations, including potential pitfalls in the diagnosis.